Taking Pictures inside a Museum to Tell a Visual Story
Photograph paintings directly (or not at an angle), use a lens that’s as normal as possible (for dSLRs, typically 40mm–60mm focal length), and don’t use a flash.
This image was shot with a 60mm focal length, ISO 6400, shutter speed 1/125, and an aperture at f/4. When shooting directly, don’t use a flash because the reflection won’t look very nice — and most museums don’t allow it, anyway. Depth of field isn’t an issue because paintings are 2-D (or flat). If a tripod had been used, which isn’t allowed in the Vatican Museum, a longer exposure at a lower ISO setting would have produced a little better image quality.