For truck drivers, here are a few websites that offer industry news, rest stop info, fuel prices, software, weather, maps, and a lot of other helpful information. Even non-truckers may want to visit a couple of these websites on occasion.

Web Site Notes
Layover.com Find industry news, opinions from regular columnists, and a job board.
DieselBoss This site offers lots of information especially for truckers, including tips on truck stops and updated diesel fuel prices, and software, such as GPS navigation systems.
Sparrow's Truck Links A handy resource for legal and business help, parts, maintenance, maps, weather, and more.
TruckNet Drivers RoundTable The main attraction here is the forum.
eTrucker This site offers everything trucking, from the latest in trucking news and events to fuel prices and routing and mileage tools.