The Heart and the Cardiac Cycle
Your heart is an impressive little organ. Even though it’s only as big as a clenched adult fist, it pumps 5 liters of blood throughout your body 70 times a minute. Your heart never stops working from the time it starts beating in the embryo until the moment you die. It doesn’t even get an entire second to rest. It beats continually every 0.8 seconds of your life.
The eight-tenths of a second that a heart beats is called the cardiac cycle. During that 0.8-second period, your heart forces blood into your blood vessels (for 0.4 seconds) and then takes a quick rest (for just 0.4 seconds). Here’s what happens in those 0.8 seconds:
Contraction of the left and right atria: This contraction squeezes blood down into the ventricles.
Contraction of the left and right ventricles: This contraction forces blood into the blood vessels that leave the heart.
Resting of the atria and ventricles: The relaxed atria allow the blood within them to drain into the ventricles.
The period of relaxation in the heart muscle is referred to as diastole, and the period of contraction in the heart muscle is called systole. If these terms sound familiar, it’s probably because you’ve heard them used in terms of blood pressure.
In a blood pressure reading, such as the normal value of 120/80 mmHg, 120 is the systolic blood pressure — the pressure at which blood is forced from the ventricles into the arteries when the ventricles contract — and 80 is the diastolic blood pressure — the pressure in the blood vessels when the muscle fibers are relaxed. The abbreviation mmHg stands for millimeters of mercury (Hg is the chemical symbol for mercury).
Answer the following practice questions on paper before continuing.
One type of heart defect is caused by a thickening and hardening of a valve so that the valve has greater resistance to blood flow. If a person’s right AV valve had this defect, what effect would it have on the flow of blood through her heart?
Another type of heart defect results when a valve doesn’t close completely, allowing blood to flow in two directions during a contraction. If a person’s pulmonary semilunar valve had this defect, what effect would it have on his health and why?
The following are the answers to the practice questions.
Blood flow would be restricted and would accumulate in the right atrium. This would increase pressure on the heart during contractions.
During the contraction of the heart, blood wouldn’t flow effectively out of the right ventricle and into the pulmonary artery. This would result in less effective oxygenation of the blood, leading to symptoms like shortness of breath and tiredness (because the person wouldn’t be getting enough oxygen).

Biology Glossary
anemia
A low number of red blood cells or low level of hemoglobin; may be caused by dietary deficiencies, metabolic disorders, hereditary conditions, or damaged bone marrow.

Biology Glossary
antigen
A foreign substance in the body that causes an immune response.

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body mass index
The BMI is the result of a formula that uses your weight and height to determine whether you need to lose weight.

Biology Glossary
carbohydrates
Energy-packed compounds consisting of carbon, hydrogen, and oxygen that provide quick fuel for organisms.

Biology Glossary
cellulose
A form of carbohydrate that has a structural role in living organisms (animals and plants).

Biology Glossary
centrifuge
A machine that is used to separate blood cells and platelets from plasma.

Biology Glossary
chloroplasts
Plant cells that use energy from sunlight to create food.

Biology Glossary
cytoplasm
The fluid contained within animal cells. Also called plasma.

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disaccharides
Carbohydrate molecules in which 2 monosaccharide molecules are joined together. Disaccharides consist of 6 to 14 carbon atoms.

Biology Glossary
DNA
Stands for deoxyribonucleic acid. Large molecules found in all living things that carry genetic information.

Biology Glossary
electron microscope
A high-powered, expensive device that uses beams of electrons to bring the finest details of cells into focus.

Biology Glossary
endocrine system
A system of glands that secrete different types of hormones that help regulate organisms.

Biology Glossary
endoplasmic reticulum
The ER is a series of canals that connects the nucleus of animal cells to the cytoplasm outside those cells.

Biology Glossary
equilibrium
The state of a chemical reaction in which the amounts on each side of the reaction have stabilized.

Biology Glossary
eukaryotes
Organisms — including plants and animals, as well as fungi, protozoa, and most algae — with cells that contain a nucleus and chromosomes.

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Golgi apparatus
A component within cells that packages and distributes hormones, enzymes, and other cell products to other organelles or outside the cell.

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hemoglobin
An iron-containing molecule in red blood cells that carries oxygen around the body.

Biology Glossary
heterotrophs
Animals — including herbivores, carnivores, and omnivores — that feed on other living organisms.

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homeostasis
The processes used by the body to constantly achieve and maintain balance.

Biology Glossary
integument
The skin or outer surface of an animal. Small animals such as earthworms use integumentary exchange to exchange gases with the environment.

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Krebs cycle
A method of describing the steps involved in the chemical process of respiration.

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lipoproteins
Compounds such as HDL and LDL that carry cholesterol through the bloodstream; made from a fat (lipid) and a protein.

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lysosomes
Specialized cellular organelles formed by the Golgi apparatus that help to clean up the cell by breaking down harmful cell products and removing dead organelles.

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maceration
A process, such as chewing, that physically breaks down food into pieces.

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matrix
The extracellular fluid in which animal cells float.

Biology Glossary
mitochondria
An organelle in animal cells that combines food with oxygen to supply energy to cells.

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monosaccharides
Carbohydrate molecules in which simple sugars consist of three to seven carbon atoms.

Biology Glossary
nuclear membrane
A two-layer structure that separates the nucleus from the cytoplasm in animal cells.

Biology Glossary
organelles
Structures that float inside the fluid of cells; used during metabolic processes.

Biology Glossary
osmosis
A mechanism that moves water and nutrients into and throughout a plant.

Biology Glossary
peristalsis
The action of food being moved down the esophagus and through the entire digestive tract.

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peroxisomes
Sacs of enzymes within animal cells that help protect the cell by breaking down accumulations of toxic products such as hydrogen peroxide.

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photosynthesis
The biochemical process that plants use to acquire energy from the sun.

Biology Glossary
plasma membrane
The membrane that holds fluid within animal cells. Also called the cell membrane.

Biology Glossary
polysaccharides
Carbohydrate molecules that are formed by many long chains of monosaccharides.

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prokaryotes
Organisms — such as bacteria and blue-green algae — with cells that do not contain a nucleus.

Biology Glossary
ribosomes
Components within cells that assist in making proteins from amino acids.

Biology Glossary
RNA
Stands for ribonucleic acid. In animals, works with DNA to produce proteins needed throughout the body.

Biology Glossary
ruminants
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