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Home > Extras > Bioinformatics For Dummies® Bonus Material
Bioinformatics For Dummies® Bonus Material
By: Jean-Michel Claverie Ph.D., Cedric Notredame Ph.D.
 

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Chapter 5: Working with a Single DNA Sequence

Chapter 5 images

Some sites for performing DNA analysis

Address Description
VecScreen_docs Screen your sequence for vector contamination
repeatmasker.genome.washington.edu Tools for detecting and masking repeats
www.firstmarket.com/cutter/cut2.html
biotools.umassmed.edu/bioapps/rsites.html
rebase.neb.com
Sites to compute restriction maps for your sequence
biotools.umassmed.edu Designing PCR primers
bioweb.pasteur.fr Tools for various DNA composition analyses
arbl.cvmbs.colostate.edu/molkit/
www.ch.embnet.org
Two sites for interactive dot-plot analysis
www.ncbi.nlm.nih.gov/gorf/gorf.html A basic ORF finder
opal.biology.gatech.edu/GeneMark
www2.ebi.ac.uk/genemark/
Gene prediction in prokaryotes using GeneMark
argon.cshl.org/genefinder/
corba.ebi.ac.uk/cgi-bin/sp/wrapper.cgi
genome.cs.mtu.edu/aat/aat.html
Various sites for predicting protein-coding genes in eukaryote DNA sequences
genes.mit.edu/genomescan For predicting complete gene structures from vertebrate DNA sequences
bio.ifom-firc.it/ASSEMBLY/assemble.html A straightforward Web-service for small-scale gene assembly
www.mrc-lmb.cam.ac.uk/pubseq/staden_home.html
www.phrap.org
www.tigr.org/software
www.acedb.org
Popular software for assembling and managing DNA sequences (you need to install them on your computer)
www.genecodes.com
www.dnastar.com
www.paracel.com
Main commercial sequence assembly software

Web Sites for searching motifs in DNA sequences

Address Description
transfac.gbf.de/TRANSFAC/ Search for potential transcriptional elements using the TRANSFAC database
bimas.dcrt.nih.gov/molbio/matrixs/ Search for transcriptional elements using the IMD database
bimas.dcrt.nih.gov/molbio/proscan/ Predict putative eukaryotic promoter regions
www.gsf.de/biodv/genomeinspector.html Detect distance correlations between sequence elements
www.dna.affrc.go.jp/htdocs/PLACE/signalscan.html Detect regulatory signals in plant sequences
meme.sdsc.edu/meme/website/ Discover motifs in groups of related DNA or protein sequences
rsat.ulb.ac.be/rsat/ Tools to analyze regulatory sequences